Statin drug therapy decreases the level of LDL (low density lipoproteins) circulating in the blood. This has been the accepted measurement for determining 'risk' of future heart disease. However consensus regarding LDL indicators for heart disease is not universal. Before statin drugs were available an 'abnormal' cholesterol measurement was determined by dividing total cholesterol by HDL cholesterol yielding the 'cholesterol/HDL Ratio.' LDL was not a determining factor in 'risk.' Statin drugs are efficient at limiting HMG-CoA, hydroxymethly gluteryl Co-A reductase, the rate-limiting step in cholesterol synthesis. Statins shut this process off thereby reducing cholesterol making.
To help determine if your cholesterol metabolism is out of recommended ranges for your age, stress level (athletes and those fight infection may have higher cholesterol) request cholesterol ratios reading versus LDL measurements.